contraindications: Contraindicated in individuals with prostate carcinoma or breast cancer.
Not indicated for use in women — virilisation risk is severe and largely irreversible.
Avoid in individuals with uncontrolled Type 2 diabetes; androgen-insulin interactions require medical supervision in this population.
Contraindicated in those with known hypersensitivity to testosterone enanthate or sesame/castor oil carrier solvents.
side_effects: Erythrocytosis — haematocrit elevation above 52% requires dose reduction.
HDL cholesterol suppression (10–15% dose-dependent reduction measured by enzymatic assay).
Oestrogen-related effects (water retention, gynaecomastia) from aromatisation — managed with aromatase inhibitors.
Androgenic effects including acne, accelerated scalp hair recession, and increased sebum production.
Temporary impaired fasting glucose in subjects with pre-existing metabolic syndrome.
monitoring: Fasting glucose and insulin (HOMA-IR) at baseline, week 4, and week 8.
Full fasting lipid panel including HDL, LDL, and triglycerides every four weeks.
Haematocrit and haemoglobin — phlebotomy indicated if haematocrit exceeds 52%.
Serum testosterone (total and free) and oestradiol mid-cycle to guide aromatase inhibitor dosing.
pct: Begin PCT approximately 14 days after the final injection to allow serum levels to decline.
Standard recovery protocol: Nolvadex (tamoxifen) 40/40/20/20 mg daily or Clomid 50/50/25/25 mg daily across four weeks.
HCG use during the cycle's final weeks can preserve Leydig-cell responsiveness and improve HPTA recovery speed.
Recheck fasting insulin and HOMA-IR four weeks into PCT to confirm metabolic normalisation alongside hormonal recovery.