contraindications: Not for use in individuals under 21 years of age.
Contraindicated in persons with pre-existing hepatic impairment, elevated liver enzymes, or a history of cholestatic jaundice.
Contraindicated in those with documented cardiovascular disease, dyslipidaemia, or uncontrolled hypertension.
Pregnancy and breastfeeding: absolute contraindication due to androgenic virilisation risk.
side_effects: Hepatotoxicity: elevated ALT/AST values are reported with 17α-alkylated oral androgens; baseline and on-cycle liver function panels are strongly recommended.
Dyslipidaemia: suppression of HDL cholesterol and elevation of LDL are pharmacologically predictable effects.
Androgenic effects: acne, accelerated scalp hair thinning, and increased sebum production are concentration-dependent.
Endogenous testosterone suppression begins within the first week of dosing due to hypothalamic-pituitary-gonadal axis feedback.
monitoring: Obtain liver function tests (ALT, AST, bilirubin) at baseline and at two-week intervals during use.
Monitor lipid panel (HDL, LDL, total cholesterol) before, mid-cycle and post-cycle.
Blood pressure measurement at each week of active dosing; methyldrostanolone is associated with transient blood pressure elevation.
Haematocrit assessment recommended for cycles exceeding four weeks.
pct: Initiate PCT within 24–48 hours of the last tablet, leveraging the 6–8-hour half-life for a clean pharmacokinetic transition.
Standard PCT agents include Tamoxifen (Nolvadex) and/or Clomiphene Citrate; duration typically 4 weeks.
Liver-support supplementation (e.g. TUDCA, NAC) should continue through PCT and for at least two weeks thereafter.
Re-assess liver enzymes and lipids six weeks after completing PCT to confirm recovery.