Contraindications: Testosterone enanthate is contraindicated in individuals with androgen-sensitive prostate or breast carcinoma, untreated obstructive sleep apnoea, active polycythaemia, or known hypersensitivity to sesame or other carrier oils used in oil-based injectable formulations. Combined use with HGH is additionally contraindicated in active malignancy due to GH-mediated IGF-1 elevation.
Side Effects: Androgenic effects include accelerated androgenic alopecia, acne, and increased sebum production. Estrogenic conversion via aromatase can produce gynecomastia and fluid retention, particularly pronounced in extended HGH cycles where GH itself contributes to water retention. Polycythaemia risk increases with cycle duration; haematocrit readings above 52% require medical review. GH co-administration may additionally elevate fasting glucose via anti-insulin mechanisms.
Monitoring: Monitor estradiol, total testosterone, haematocrit, liver enzymes (ALT/AST), lipid panel, and IGF-1 at baseline, week 8, and week 16 of any combined cycle. Blood pressure should be checked monthly; GH-related fluid retention can elevate systolic values independent of testosterone dose. Adjust aromatase inhibitor dosing based on confirmed estradiol values, not symptoms alone.
PCT: Begin SERM-based PCT (Tamoxifen or Clomiphene) approximately 14 days after the final Enanthate 300 injection. A standard PCT runs 4–6 weeks. If HGH is continued post-testosterone, IGF-1 monitoring should continue throughout PCT to detect any interference with HPTA recovery signalling. Run bloodwork confirming LH, FSH, and total testosterone recovery before discontinuing PCT.