Contraindications: Mesviron 25 is contraindicated in individuals with androgen-sensitive neoplasms, existing hepatic impairment, hypercalcaemia, or a known hypersensitivity to mesterolone or any tablet excipient. Not for use by women, particularly women of childbearing potential, due to virilisation risk. Individuals with a history of prostate conditions should obtain urological clearance before initiating any androgen-containing product.
Side Effects: Mesterolone at doses used in PCT is generally well tolerated, but androgenic effects — including increased sebum production, acne on the upper back or shoulders, and accelerated scalp hair thinning in genetically predisposed users — may occur. Libido changes (usually increased early in PCT) are common and typically normalise as endogenous hormone levels recover. Mood effects are generally mild at standard PCT doses.
Monitoring: A baseline blood panel covering total testosterone, free testosterone, LH, FSH, SHBG, haematocrit, and hepatic enzymes (ALT/AST) should be obtained before starting PCT. Repeat at week 3 and at protocol completion (week 6 or 8). Haematocrit monitoring is particularly relevant for individuals who experienced erythropoietic stimulation during their cycle.
PCT: Mesviron 25 is a PCT support agent, not a gonadotropin stimulator; it must be paired with a SERM (tamoxifen or clomiphene) during moderate-cycle PCT to address the central axis. Do not rely on mesterolone alone as the sole PCT intervention following a moderate suppressive cycle. Discontinue if any unexpected androgenic or cardiovascular changes occur and seek medical evaluation.