Contraindications: Trestolone Acetate is contraindicated in individuals with existing androgen-sensitive malignancies, elevated haematocrit above 54%, severe hepatic impairment, or untreated sleep apnoea. Do not use if you are currently taking anticoagulant therapy without explicit medical supervision. Women of childbearing potential must not use this compound due to virilisation risk.
Side Effects: Androgenic effects include accelerated scalp hair thinning, acne, and potential prostate stimulation. Trestolone Acetate aromatises significantly — users should anticipate oestrogen-related effects including water retention and gynecomastia risk; an aromatase inhibitor (e.g., anastrozole or letrozole) should be on hand. Suppression of endogenous testosterone production is rapid and pronounced with daily dosing protocols.
Monitoring: Obtain a full blood panel — including LH, FSH, total testosterone, haematocrit, liver enzymes (AST/ALT), and lipid profile — at baseline and at four-week intervals during the cycle. Serum oestradiol should be monitored to guide aromatase inhibitor dose adjustments. Blood pressure measurement twice weekly is advisable given the compound's propensity for fluid retention at higher doses.
PCT: Begin SERM-based post-cycle therapy (tamoxifen 20–40 mg/day or clomiphene 50 mg/day) 3–5 days after the final injection, timed to align with plasma clearance of the acetate ester. A minimum four-week PCT duration is recommended; HCG 500 IU every other day during the final week of the cycle may accelerate testicular recovery. Follow-up bloodwork at eight weeks post-PCT is advised to confirm endogenous axis restoration.