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Cardarine (GW-501516) 10mg/tab 60 Tablets by Master Pharma
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Cardarine (GW-501516) 10mg/tab 60 Tablets by Master Pharma

Master Pharma Cardarine (GW-501516) is a PPARδ agonist research compound supplied as 10 mg tablets, with a 60-tablet count sized to cover a full structured cycle under standard dose-and-time-off protocols. Each tablet delivers the entry dose most frequently referenced in research literature, making dose escalation across multi-week phases straightforward without tablet splitting. Batch release is governed by lot-specific HPLC potency verification and LAL endotoxin quantification — both results recorded on a traceable Certificate of Analysis issued per production lot.

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  • 10 mg/tab unit enables clean dose escalation from 10 to 20 mg without tablet splitting
  • 60-tablet count precisely covers a standard eight-week research cycle at 10 mg/day with buffer
  • PPARδ agonism drives fatty-acid oxidation gene expression without engaging androgen receptors
  • No HPTA suppression means no hormonal recovery agent is required during the off period
  • Once-daily administration supported by the compound's 16–24 hour pharmacokinetic half-life
  • Lot-specific HPLC and LAL data on the Certificate of Analysis confirm potency and endotoxin safety
  • GMP-aligned tablet manufacturing ensures consistent active-content delivery across the full 60-tablet supply

Key takeaways

  • Plan your GW-501516 cycle as eight weeks on, four weeks off minimum.
  • Start dosing at 10 mg/day before escalating to 20 mg mid-cycle.
  • Confirm each batch with the lot-specific HPLC and LAL Certificate of Analysis.
  • Expect once-daily dosing based on the compound's 16–24 hour half-life.
  • Choose 10 mg/tab to maintain precise escalation control without tablet splitting.

What GW-501516 Is and Why Dose Architecture Matters

Master Pharma Cardarine (GW-501516) is a synthetic PPARδ agonist whose research utility is most clearly expressed when administered according to a defined dose escalation and time-off schedule rather than at a single fixed quantity throughout. The compound activates peroxisome proliferator-activated receptor delta, upregulating gene networks that govern fatty-acid oxidation and mitochondrial substrate management. Because GW-501516 carries no androgen-receptor affinity, it does not suppress the hypothalamic–pituitary–testicular axis — a property that distinguishes its cycle-planning requirements from those of androgenic compounds.

Standard Dose Ranges Referenced in Research

Research literature consistently places GW-501516 dose ranges between 10 mg and 20 mg per day, with 10 mg representing the most common starting point for an eight-week observation period. Compared to higher single-dose formats available from other suppliers, the 10 mg/tab unit from Master Pharma allows researchers to begin at the conservative end and step to 20 mg in week three or four without reformulating the protocol. The 60-tablet count supports exactly this structure: eight weeks at 10 mg/day consumes 56 tablets, leaving a four-tablet buffer, while a two-week escalation to 20 mg/day within the same pack fits a tiered schedule without mid-cycle reorder.

Cycle Length and Time-Off Planning

The most widely applied research cycle length for GW-501516 is eight weeks on, followed by a minimum four-week washout period before resumption. Some protocols extend to twelve weeks at 10 mg/day for continuous endurance-output observation, though the eight-week structure remains the benchmark most cited in peer-reviewed animal research. GW-501516 carries an approximate 16–24 hour half-life (confirmed by plasma pharmacokinetic studies in preclinical models), meaning once-daily dosing maintains consistent receptor occupancy without accumulation overshoot during multi-week protocols.

Quality Infrastructure Behind Every Tablet

Master Pharma's tablet manufacturing operates under GMP-aligned release criteria: active content per tablet is confirmed by HPLC against a certified reference standard, and endotoxin burden is quantified by LAL assay prior to batch release. Both values are recorded on the lot-specific Certificate of Analysis — the batch number printed on the outer packaging corresponds directly to the COA on file, allowing full traceability from production to dispatch.

Usage

  1. Determine your starting dose — 10 mg/day (one tablet) is the standard research entry point and the dose supported by the widest body of preclinical data.
  2. Take one tablet once daily at the same time each day; the 16–24 hour half-life means timing consistency maintains stable receptor occupancy.
  3. Log the cycle start date and plan the eight-week end date before beginning; note the mandatory four-week off period in the same schedule.
  4. At week two or three, assess whether escalation to 20 mg/day (two tablets) is appropriate for the research objective; document the dose change date.
  5. Store remaining tablets in the original container with desiccant at 15–25 °C, away from moisture and direct light; no refrigeration is required.
  6. At cycle end, begin the minimum four-week washout phase; because GW-501516 is not androgenic, no post-cycle hormonal support protocol is required — simply observe the off-period before restarting.

Warnings

Contraindications: GW-501516 is a research compound not approved for human therapeutic use by any regulatory authority. It is contraindicated for individuals with active hepatic conditions, those under 18, pregnant or nursing individuals, and anyone with a history of hormone-sensitive conditions. Preclinical rodent studies at supratherapeutic dose levels identified accelerated tumour development — researchers should factor this finding into experimental design and duration decisions.

Side Effects: Reported observations in research settings include transient gastrointestinal discomfort at higher dose ranges, elevated LDL/HDL ratio shifts in lipid panels, and occasional headache during early-cycle initiation. Unlike androgenic compounds, virilisation-related effects are not expected given the absence of androgen-receptor activity.

Monitoring: Lipid panel (total cholesterol, LDL, HDL, triglycerides) should be measured at baseline and at the end of the active cycle. Liver enzyme markers (ALT, AST) are recommended as part of routine cycle monitoring. Dose should not exceed 20 mg/day; extending cycle length beyond twelve weeks without a structured washout is not supported by current research data.

PCT: Post-cycle therapy agents targeting HPTA recovery are not required following a GW-501516-only protocol, as the compound does not suppress testosterone production via androgen-receptor pathways. The four-week off period is a compound-exposure break, not a hormonal recovery phase.

Frequently asked questions

What is the standard cycle length for GW-501516 in research protocols?
The most referenced cycle length for GW-501516 is eight weeks, followed by a four-week off period before any repeat cycle. Some extended research protocols run twelve weeks at the lower 10 mg/day dose. The eight-week structure is the benchmark most consistently cited in published preclinical literature and is the format the Master Pharma 60-tablet count is sized to support.
What dose range is typically used in GW-501516 research, and how does 10 mg/tab help with escalation?
Research protocols most commonly begin at 10 mg/day and escalate to 20 mg/day mid-cycle if the lower dose is well tolerated. The 10 mg/tab format from Master Pharma makes this escalation clean: the researcher simply moves from one tablet daily to two, with no splitting or liquid measuring required. This precision is especially useful in structured multi-phase eight-week designs.
How long should the break be between GW-501516 research cycles?
A minimum four-week washout is the most widely applied off-period between GW-501516 cycles in research settings. Because GW-501516 does not suppress the HPTA, post-cycle therapy agents are not required for hormonal recovery — the off-period is instead intended to limit cumulative compound exposure and allow baseline re-establishment before the next observation phase.
Why does Master Pharma offer Cardarine at 10 mg/tab rather than a higher concentration?
The 10 mg/tab concentration is the lowest in the current Cardarine group and serves a specific research function: it is the most precise entry point for dose-escalation protocols. Starting at 10 mg/day and stepping up to 20 mg/day is a controlled escalation supported by a single SKU. Higher-concentration tablets require splitting to achieve the same starting dose, introducing measurement variability that the 10 mg unit eliminates.
How should Master Pharma Cardarine tablets be stored, and does opening the container affect stability?
Tablets should be stored in a cool, dry location away from direct light, ideally between 15–25 °C. Once the container is opened, the desiccant already present in the packaging helps maintain low humidity around the remaining tablets. Oral solid-dose formats are inherently more stable post-opening than liquid preparations — no refrigeration is required, and the 60-tablet supply can be used across a full eight-week cycle without concern about degradation under correct ambient storage. (2) angle_used

Manufacturer

Master Pharma's market position among oral SARM tablet suppliers is defined primarily by one consistently cited differentiator: batch-level analytical accountability that covers the full product range rather than selected high-visibility SKUs only. For the Cardarine 10 mg/tab line, this means every dispatched lot carries a Certificate of Analysis generated from two independent analytical events — HPLC active-content confirmation against a traceable reference standard, and LAL endotoxin quantification against established safety thresholds. The batch number on the outer label maps directly to both data sets, giving the receiving researcher a complete release record rather than a product-level specification sheet. This level of documentation infrastructure is unusual at the price point Master Pharma occupies and is the primary reason the brand maintains consistent placement among top-selling oral research compounds in competitive European and international distribution channels.

Product details

BrandMaster Pharma
Active ingredientcardarine
Also known asEndurobol, Cardarine (GW-501516), Master Pharma Endurobol
Strength10 mg
FormTabletten
Pack size60 pieces
Item numberSARM-CARD-MAS-004

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