contraindications: Not indicated for pre-menopausal women or individuals with known hypersensitivity to anastrozole or any excipient component.
Not suitable for use during an active anabolic cycle when high-dose aromatising androgens are still being administered at suppressive levels.
Avoid concurrent use with oestrogen-containing compounds, as these directly negate CYP19A1 inhibition.
side_effects: Oestradiol suppression below physiological range: joint stiffness, reduced libido, mood disturbance — monitor with sensitive immunoassay.
Potential impact on bone mineral density with prolonged use; relevant for extended PCT protocols exceeding twelve weeks.
Headache, hot flushes, and mild gastrointestinal upset reported in a subset of users; typically transient and dose-dependent.
monitoring: Oestradiol (sensitive assay), LH, FSH, and total testosterone: baseline, midpoint, and endpoint of every PCT protocol.
Bone metabolism markers advisable if anastrozole use extends beyond twelve weeks continuously.
Liver function panels recommended for users concurrently using hepatotoxic oral compounds.
pct: PCT duration must be governed by laboratory data — do not discontinue anastrozole based on subjective wellbeing alone.
SERM co-administration (e.g. tamoxifen) should be sequenced rather than overlapped with anastrozole; co-administration may affect anastrozole plasma exposure.
Confirm HPG axis restoration with a final bloodwork panel at least two weeks after the last anastrozole tablet before concluding the recovery phase.