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MT-2 10mg/vial 1 Vial by Bio-Peptide
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MT-2 10mg/vial 1 Vial by Bio-Peptide

4.5 (2 reviews)

MT-2 (Melanotan 2) is a synthetic cyclic heptapeptide analogue of alpha-melanocyte-stimulating hormone (α-MSH) engineered to activate MC1R for eumelanin-driven skin darkening, MC3R/MC4R for appetite reduction, and central MC4R pathways for libido enhancement — all within a single 10 mg lyophilised vial format. Bio-Peptide formulates MT-2 as a lyophilised powder at 10 mg per vial, a quantity that accommodates both conservative sub-milligram loading schedules and reduced-frequency maintenance phases without reformulation. Each batch clears two independent laboratory gates before release: HPLC analysis locks in sequence identity and purity, while LAL endotoxin screening certifies microbiological safety to injection-grade standards.

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  • Stimulates MC1R-mediated eumelanin production for a natural-looking tan without prolonged UV exposure
  • Activates hypothalamic MC4R pathways to enhance libido in both male and female users
  • Exerts a dose-dependent appetite-suppressing effect, supporting leaner body composition during a tanning protocol
  • Longer active half-life than endogenous α-MSH due to cyclic peptide structure resisting enzymatic breakdown
  • 10 mg lyophilised format allows flexible dosing from 0.25 mg loading phases through to low-dose maintenance
  • Every batch independently verified by HPLC sequence analysis and LAL endotoxin screening before release
  • Single-ingredient formulation with no excipient interference, enabling clean dose-response tracking

Key takeaways

  • Target three effects simultaneously: tanning, libido, and appetite suppression.
  • Start with a 0.25 mg loading dose to assess individual tolerance first.
  • Combine minimal UV exposure during loading to amplify eumelanin production.
  • Refrigerate reconstituted MT-2 and use within four weeks of opening.
  • Verify every vial's batch certificate for HPLC purity and LAL endotoxin status.

Melanotan 2: A Melanocortin Agonist With Three Mechanisms of Action Explained

Melanotan 2 is a stabilised, cyclic synthetic analogue of the endogenous hormone α-MSH, engineered to bind melanocortin receptors with greater potency and a longer active half-life — estimated at 1–2 hours versus minutes for the native peptide — making it one of the few research compounds documented to influence pigmentation, central appetite regulation, and sexual function through a single molecular target class. Bio-Peptide's 10 mg lyophilised vial delivers this compound in a dry, stable form that retains integrity for extended periods when refrigerated.

How MT-2 Drives UV-Independent Tanning

MT-2 activates MC1R receptors located on dermal melanocytes, stimulating the production and redistribution of eumelanin — the brown-black pigment responsible for a natural-appearing tan. Compared to alpha-MSH itself, Melanotan 2 requires significantly lower doses to produce equivalent melanocyte stimulation, owing to its cyclic peptide structure which resists enzymatic degradation. Clinical tanning studies have documented visible pigmentation responses in Fitzpatrick skin types I–IV within two to four weeks of subcutaneous administration at doses ranging from 0.25 mg to 1 mg per injection. Minimal UV exposure during this loading phase amplifies the eumelanin response without the cumulative DNA damage of conventional sunbed use.

Central Effects: Libido Activation and Appetite Suppression

MT-2 acts on MC4R receptors in the hypothalamus to trigger two distinct central nervous system effects that set it apart from topical or UV-based tanning methods. First, hypothalamic MC4R activation initiates pro-erectile and pro-sexual signalling in both male and female subjects — a mechanism documented in pharmacological literature as early as Wessells et al. (1998). Second, the same hypothalamic MC4R pathway mediates appetite suppression by reducing caloric intake, a property that has attracted research interest independent of the compound's cosmetic applications. These dual central effects mean MT-2 influences body composition indirectly alongside its primary cosmetic role.

Quality Assurance: HPLC Identification and LAL Endotoxin Testing

Every Bio-Peptide MT-2 batch passes through two independent laboratory verification steps before release. HPLC (High-Performance Liquid Chromatography) analysis confirms sequence identity and purity percentage at the batch level, producing a certificate of analysis specific to that production run. A separate LAL (Limulus Amebocyte Lysate) endotoxin screen verifies that bacterial endotoxin levels fall within injection-grade safety limits. Both tests are conducted externally, not by internal QC staff, ensuring unbiased verification of every vial that reaches the end user.

Usage

  1. Gather supplies: Bio-Peptide MT-2 10 mg vial, bacteriostatic water, 29–31 gauge insulin syringes, alcohol swabs, and a sharps disposal container.
  2. Reconstitute by injecting 1–2 mL of bacteriostatic water slowly along the inner vial wall using an insulin syringe; swirl gently for 30 seconds until the lyophilised powder dissolves completely — never vortex or shake vigorously.
  3. Calculate your dose: with 2 mL reconstitution volume, every 0.1 mL drawn = 0.5 mg MT-2; for a 0.25 mg starting dose, draw 0.05 mL into a fresh syringe.
  4. Select a subcutaneous injection site — lower abdomen or outer thigh — swab with an alcohol wipe, allow to air-dry, then pinch the skin and insert the needle at a 45-degree angle; inject slowly and withdraw.
  5. Administer your first loading doses in the evening to reduce the likelihood of nausea; plan brief, 10–15 minute outdoor UV exposure during daylight hours the following day to synergise with MC1R melanocyte activation.
  6. After each use, recap the vial, label it with the reconstitution date, and store refrigerated at 2–8 °C; use within 4 weeks and inspect for particulates or colour change before every injection — discard if either is observed.

Warnings

Contraindications: MT-2 is not suitable for individuals with a personal or family history of melanoma, atypical mole syndrome, or any active pigmented skin lesion requiring dermatological monitoring. Individuals with cardiovascular conditions or those taking medications affecting blood pressure should not use MT-2 without prior medical consultation, as transient blood pressure fluctuations have been reported. Pregnancy and breastfeeding are absolute contraindications.

Side Effects: Commonly reported effects include transient nausea (particularly pronounced at doses above 0.5 mg), facial flushing, spontaneous erections in male users, fatigue, and yawning — most of which diminish after the first 1–2 weeks of loading. Darkening of existing moles or freckles may occur due to non-selective MC1R activation across all melanocytes. New or rapidly changing skin lesions must be assessed by a dermatologist promptly.

Monitoring: Conduct a full skin examination before beginning any MT-2 protocol and photograph all moles and pigmented lesions as a baseline reference. Re-examine the skin monthly during active use; any lesion demonstrating asymmetry, border irregularity, colour variation, or diameter increase warrants immediate dermatological review. Blood pressure should be checked periodically, particularly during the loading phase.

PCT: MT-2 does not suppress the hypothalamic-pituitary-gonadal (HPG) axis and therefore does not require post-cycle therapy in the conventional sense. Libido effects resolve naturally within days of discontinuation. If MT-2 is used alongside hormonal compounds that do require PCT, the MT-2 cessation schedule should be planned independently and does not influence the hormonal recovery timeline.

Frequently asked questions

How quickly does Melanotan 2 produce a visible tan without sunbeds?
Most users report noticeable pigmentation darkening within 2–4 weeks of daily subcutaneous loading doses of 0.25–0.5 mg, combined with brief, incidental UV exposure such as 10–15 minutes of natural sunlight. Fitzpatrick skin types I–II typically require the longer end of this range. The tan develops gradually as eumelanin production and redistribution increase in dermal melanocytes following MC1R activation.
What effect does Melanotan 2 have on libido and how does that mechanism work?
MT-2 enhances libido by binding MC4R receptors in the hypothalamus, initiating pro-sexual CNS signalling in both sexes. In male subjects, this pathway has been shown to facilitate spontaneous erections independent of arousal stimuli, a finding documented in peer-reviewed pharmacological research since the late 1990s. The effect is typically noticed within the first few days of administration and is considered a predictable pharmacological outcome rather than a side effect.
Can Melanotan 2 suppress appetite, and is that effect dose-dependent?
Yes — MT-2 reduces appetite through hypothalamic MC4R agonism, the same receptor pathway responsible for its libido effects. The appetite-suppressing response appears dose-dependent: users administering doses above 0.5 mg commonly report reduced hunger for several hours post-injection. At standard maintenance doses of 0.25 mg, appetite suppression is mild and transient, making caloric management relatively straightforward during a tanning protocol.
How do you reconstitute and store a 10mg MT-2 vial after opening?
Reconstitute the lyophilised MT-2 powder by injecting 1–2 mL of bacteriostatic water into the vial using a standard insulin syringe, directing the stream along the vial wall to avoid foaming. Swirl gently — never shake. Once reconstituted, store the vial refrigerated at 2–8 °C; it remains stable for up to 4 weeks. Discard any unused solution showing particulate matter or discolouration.
What syringe type is recommended for MT-2 injections and how is the dose measured?
A 29–31 gauge insulin syringe (0.3 mL or 1 mL capacity) is the standard tool for subcutaneous MT-2 administration. With a 2 mL reconstitution volume from a 10 mg vial, each 0.1 mL drawn equals 0.5 mg of MT-2. For a 0.25 mg loading dose, draw 0.05 mL. Injection sites include the abdomen or outer thigh; rotate sites to minimise localised irritation and subcutaneous nodule formation. (2) angle_used

Manufacturer

The foundation of Bio-Peptide's approach to the research-peptide market can be traced to a single, commercially inconvenient constraint its founders chose to build into the company's release process before a single product reached the public: independent laboratory sign-off was mandatory — not aspirational. That constraint meant two specific external checks had to clear for every batch. HPLC (High-Performance Liquid Chromatography) had to confirm the compound's molecular sequence and register an acceptable purity percentage. A separate LAL (Limulus Amebocyte Lysate) endotoxin assay had to certify that bacterial contamination levels fell within injection-grade tolerances. Neither check could be substituted by internal testing, and neither could be waived on logistical or cost grounds. The result is a batch-specific certificate of analysis accompanying every vial — not a generalised quality statement, but a document tied to the exact production run from which that vial originated. This structure was not designed in response to regulatory pressure; it preceded any formal external scrutiny of the European research-compound sector and reflected a founding judgement that the field's credibility problem was, at its core, a verification problem.

Product details

BrandBio-Peptide
Active ingredientmelanotan 2
Also known asMelanotan II, MT-2, Melanotan 2, Bio-Peptide Melanotan II
Strength10 mg
FormVial
Pack size1 piece
Item numberPEPT-MEL2-BIO-001

Reviews

4.5/5

2 reviews

  • Rating: 5 out of 5 starsassassinVerified purchase

    proper colour, solid erections

    Running 0.5mg EOD for 3 weeks. tan came in around day 10, noticeably darker by week 2. libido went through the roof which I wasn't expecting to be that strong. Discretely packed, arrived in 5 days. Reconstituted clean, no floaties. Genuinely impressed with Bio-Peptide on this one

  • Rating: 4 out of 5 starsmidnight25Verified purchase

    good results, bit of nausea

    tan is real and the spontaneous erections are no joke lol. Dosed at 0.25mg to start and worked up to 0.5mg. Only gripe is the nausea first few shots had me feeling rough for an hour or two each time. Settled down after week 1 though. Would buy again, just start low lads

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