contraindications: Contraindicated in individuals with diagnosed prostate or breast carcinoma.
Not suitable for women of childbearing potential due to virilisation risk at performance doses.
Avoid use if a history of polycythaemia or significant hepatic impairment is present.
Individuals currently on anticoagulant therapy should consult a physician before use, as androgens may potentiate anticoagulant effects.
side_effects: Androgenic: accelerated scalp hair thinning in genetically predisposed individuals; increased sebaceous gland activity (acne).
Cardiovascular: suppression of HDL cholesterol during the cutting cycle; haematocrit elevation with prolonged use.
Endocrine: dose-dependent suppression of the hypothalamic-pituitary-gonadal (HPG) axis requiring structured post-cycle recovery.
Mood: heightened aggression or irritability reported at higher androgenic loads — monitor during contest-prep stress periods.
monitoring: Full blood count (FBC) and lipid panel at baseline and at mid-cycle (week 5–6) during a 10–12 week cutting phase.
Blood pressure monitoring every two weeks; androgen use can elevate systolic pressure, particularly during caloric restriction.
Haematocrit should remain below 52%; values above this threshold warrant dose reduction or cycle cessation.
pct: Begin PCT with a SERM (Nolvadex 40/40/20/20 mg or Clomid 50/50/25/25 mg, daily, across four weeks) approximately 5–7 days after the final Mastelad injection.
HCG (500 IU every other day for 10 days pre-PCT) is recommended following cycles of 10 weeks or longer to restore testicular responsiveness before SERM therapy.
Retest serum testosterone and LH/FSH at four weeks post-PCT completion to confirm HPG axis recovery.