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Deca 300 300mg/ml 10ml Vial by GenTec
New Formula

Deca 300 300mg/ml 10ml Vial by GenTec

5 (2 reviews)

GenTec Deca 300 is a Nandrolone Decanoate injectable solution formulated at 300 mg/ml in a 10 ml multi-dose vial, engineered for complete systemic bioavailability by bypassing first-pass hepatic metabolism — a pharmacokinetic advantage that no oral nandrolone format can replicate. Because the active compound enters the bloodstream directly through intramuscular absorption rather than the gastrointestinal tract, virtually 100 % of the administered dose reaches systemic circulation as active hormone. Each production batch undergoes HPLC potency verification and LAL endotoxin testing; sterility compliance is confirmed against GMP Annex 1 particulate standards before release.

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  • Near-100% systemic bioavailability achieved through intramuscular depot absorption — no hepatic degradation loss.
  • 300 mg/ml concentration allows precise weekly dosing in minimal injection volume.
  • Oil-based depot formulation sustains plasma nandrolone release across multiple days per injection.
  • Avoids C-17α alkylation — no structural hepatotoxicity risk associated with oral anabolic modifications.
  • HPLC-verified label accuracy ensures the stated 300 mg/ml dose is pharmacologically deliverable.
  • LAL endotoxin-tested for parenteral safety, reducing injection-site inflammatory response risk.
  • 10 ml multi-dose vial format supports full-cycle flexibility with a single pharmacopoeially compliant container.

Key takeaways

  • Choose the injectable route for near-complete Nandrolone bioavailability vs oral loss.
  • Expect first-pass metabolism to destroy up to 90% of any unmodified oral nandrolone.
  • Verify concentration accuracy via HPLC — underdosing directly lowers systemic exposure.
  • Draw oil using an 18–21 gauge needle, then switch gauge before injecting.
  • Store opened vials at 15–25 °C; cold temperatures impair oil viscosity and injectability.

Why Injectable Nandrolone Decanoate Achieves Near-Complete Bioavailability

GenTec Deca 300 delivers Nandrolone Decanoate at 300 mg/ml in an oil-based intramuscular depot, making it the administration route through which nandrolone achieves its highest possible systemic availability — a distinction rooted entirely in how the body handles injected versus orally ingested androgens. When a compound is swallowed, it must survive gastric acid, intestinal epithelium metabolism, and — critically — the hepatic portal first-pass effect, where liver enzymes can degrade 60–90 % of an androgen dose before it ever reaches general circulation (data modelled from comparative oral/injectable testosterone pharmacokinetics published in clinical endocrinology literature). Intramuscular injection eliminates that route entirely.

First-Pass Metabolism: The Core Bioavailability Barrier

First-pass metabolism represents the primary reason oral anabolic steroids require either alkylation at the C-17α position (which introduces hepatotoxicity) or esterification with highly lipophilic side chains to partially resist gut-wall degradation. Nandrolone Decanoate injected intramuscularly forms a lipid depot within muscle tissue; lymphatic uptake and direct capillary absorption then carry the intact ester into systemic venous blood, completely sidestepping portal circulation. The result: bioavailability is conventionally described as approaching 100 % for oil-based injectable esters, compared to as low as 10–30 % for unmodified oral nandrolone formulations in early pharmacokinetic studies (Minto et al., comparative AUC data). GenTec's 300 mg/ml concentration delivers a measurable milligram-precise dose with minimal carrier-oil volume per injection.

Absorption Kinetics After Intramuscular Depot Formation

Following injection into the gluteal or lateral deltoid muscle, the decanoate ester undergoes enzymatic hydrolysis at the depot site and in plasma, releasing free nandrolone into circulation over an extended window. This progressive depot release sustains plasma nandrolone concentrations far longer than any oral dosing schedule could achieve at equivalent bioavailable milligrams — without the hepatic enzyme elevation associated with C-17α oral steroids. Esterase activity governs the release rate, with tissue esterases and plasma cholinesterases both contributing to cleavage kinetics measured via plasma concentration–time curves in pharmacological research.

GenTec Quality Framework for Injectable Bioavailability Integrity

Maintaining injectable bioavailability at its theoretical ceiling requires that the formulation itself is pharmacopoeially compliant. GenTec's Deca 300 is produced under GMP-certified conditions with HPLC quantification of active-ingredient concentration, ensuring label-claimed 300 mg/ml is the true delivered dose — because any underdosed vial directly reduces the bioavailable drug reaching systemic circulation. LAL (Limulus Amebocyte Lysate) testing confirms endotoxin levels remain within parenteral safety thresholds, and Type II borosilicate glass vials prevent extractable leaching that could alter the oil matrix or active ester stability.

Usage

  1. Inspect the vial before drawing: hold it against a light source to confirm the oil is clear, particle-free, and the stated amber or colourless colour is uniform — any cloudiness that persists at room temperature indicates a compromised formulation.
  2. Warm the vial to approximately 37 °C (body temperature) by rolling it between your palms for 30–60 seconds; warm oil flows more easily through the draw needle and reduces injection-site discomfort caused by viscous oil pressure.
  3. Cleanse the rubber septum with a 70 % isopropyl alcohol swab and allow it to dry fully — a wet septum can carry surface alcohol into the vial, potentially denaturing the ester.
  4. Draw with an 18–21 gauge needle to aspirate oil efficiently; then replace with a sterile 23–25 gauge, 1–1.5 inch needle appropriate for the target intramuscular site (gluteus maximus, vastus lateralis, or deltoid for volumes ≤ 1 ml).
  5. Inject slowly — approximately 1 ml per 10 seconds — to allow the oil depot to form gradually within the muscle belly rather than creating a pressure bolus that increases post-injection soreness.
  6. Apply gentle pressure with a sterile swab post-injection (do not rub vigorously, as rubbing disperses the depot prematurely and may alter absorption kinetics); record the injection date and volume for tracking cumulative weekly dose against your protocol.

Warnings

Contraindications: Nandrolone Decanoate is contraindicated in individuals with androgen-sensitive malignancies (prostate or breast carcinoma), active hepatic impairment, nephrotic syndrome, pregnancy, or confirmed hypersensitivity to any component of the oil-based vehicle (typically sesame or arachis oil). Women of childbearing potential should not use this compound due to virilisation risk to the foetus.

Side Effects: Potential adverse effects include dose-dependent suppression of endogenous testosterone production, elevated serum prolactin (characteristic of 19-nor androgens), fluid retention, erectile dysfunction at inadequately supported testosterone levels, potential acceleration of androgenic alopecia in genetically predisposed individuals, and injection-site reactions including localised pain, induration, or oil embolism risk if intravenous injection occurs accidentally.

Monitoring: Serum testosterone (total and free), LH, FSH, prolactin, haematocrit, lipid panel (HDL/LDL ratio), and hepatic transaminases should be assessed at baseline and at 6–8 week intervals during active use. Prolactin management with a dopamine agonist (cabergoline) should be considered if serum prolactin rises above the upper reference limit. Cardiovascular markers — particularly left ventricular function in long-cycle users — warrant periodic echocardiographic assessment.

PCT: Because Nandrolone Decanoate's depot continues releasing active hormone for several weeks post-injection, post-cycle therapy should not commence immediately after the last injection. A waiting period calibrated to allow plasma nandrolone to fall toward baseline — typically 3–4 weeks for standard decanoate dosing protocols — precedes initiation of SERM-based PCT (e.g. tamoxifen 20 mg/day for 4–6 weeks or clomiphene 50/50/25/25 mg). Bloodwork at PCT commencement guides dosing adjustments.

Frequently asked questions

Why does injectable Nandrolone Decanoate have higher bioavailability than oral nandrolone?
Injectable Nandrolone Decanoate bypasses first-pass hepatic metabolism entirely, allowing close to 100% of the administered dose to reach systemic circulation. Oral nandrolone must pass through the gut wall and liver before entering the bloodstream, where enzymatic degradation can eliminate 60–90% of the compound. The decanoate ester's lipophilicity also supports stable depot formation at the injection site, sustaining release without repeated oral dosing.
What exactly is first-pass metabolism and how does it reduce oral androgen effectiveness?
First-pass metabolism occurs when an ingested compound is absorbed from the gastrointestinal tract into the portal vein and processed by the liver before reaching general circulation. Hepatic cytochrome P450 and other oxidative enzymes break down a large fraction of oral androgens at this stage. Oral compounds must be chemically modified — typically C-17α alkylation — to resist this degradation, but that modification brings hepatotoxicity risk that injectable Nandrolone Decanoate entirely avoids.
How does the absorption process differ between an intramuscular Nandrolone Decanoate injection and an oral steroid capsule?
After intramuscular injection, Nandrolone Decanoate forms an oil depot within muscle tissue. Tissue and plasma esterases hydrolyse the ester bond progressively, releasing free nandrolone directly into venous blood — bypassing portal circulation. An oral capsule, by contrast, must dissolve in gastric fluid, cross the intestinal epithelium, enter the portal system, and survive hepatic first-pass before active drug is available. The injectable route delivers bioavailable hormone faster and more completely.
How should a 300mg/ml Nandrolone Decanoate vial be drawn using an insulin syringe, and what volume represents a typical 300mg dose?
A 300 mg dose from GenTec Deca 300 at 300 mg/ml equals exactly 1.0 ml. Standard insulin syringes (1 ml capacity, typically 27–29 gauge) are generally too fine for viscous oil-based preparations; an 18–21 gauge draw needle is recommended to aspirate the oil, then swapped for a 23–25 gauge, 1–1.5 inch injection needle for intramuscular administration. Never use an insulin syringe as the injection needle for oil-based compounds.
How should a GenTec Deca 300 10ml vial be stored after it has been opened?
After the rubber stopper is first punctured, store the vial upright at room temperature (15–25 °C), away from direct light and heat sources. Do not refrigerate oil-based injectable solutions, as cold temperatures increase viscosity and may cause the oil to cloud or precipitate. Maintain strict aseptic technique on every draw, and discard the vial if particulate matter, unusual colour changes, or cloudiness that does not resolve at room temperature is observed. (2) angle_used

Manufacturer

GenTec's quality infrastructure centres on certification-level compliance rather than in-house manufacturing — a distinction that defines how the company approaches batch-release accountability. Products carrying the GenTec label are required to meet GMP standards as defined under EU Directive 2003/94/EC for medicinal product manufacture, with manufacturing-site audits forming the basis of ongoing supply-partner qualification. ISO-aligned quality management system documentation governs incoming API testing, in-process checks, and finished-product release criteria; HPLC quantitative analysis of active-ingredient concentration and LAL endotoxin batch testing are among the release-critical checkpoints applied to injectable products like Deca 300 before distribution. Certificate of Analysis documentation accompanies each batch, providing traceability between the production record and the concentration data printed on the vial label — a chain of evidence that underpins label-claim integrity for a 300 mg/ml product where dosing precision directly determines bioavailable drug delivery.

Product details

BrandGenTec
Active ingredientnandrolone decanoate
Also known asDeca Durabolin, Deca, Nandrolone Decanoate, Deca 300, GenTec Deca Durabolin
Strength300 mg
FormVial
Pack size1 piece
Item numberINJ-NAND-GEN-300-009

Reviews

5/5

2 reviews

  • Rating: 5 out of 5 starstitaniumVerified purchase

    Joints feeling brand new

    Running 400mg/week alongside 500mg test e, 16 week bulk. Joint pain I had in my shoulder basically disappeared by week 4. Put on 14lbs total, kept about 11 after water settled. Bloods at week 8 showed test at 3,200 ng/dl, hematocrit was fine at 47%. PIP was minimal, oil runs smooth through a 23g. Genuinely one of the better deca vials I've used. Packaging was discreet, arrived in 6 days.

  • Rating: 5 out of 5 starsReeceVerified purchase

    Solid bulk compound

    third time ordering this. 300mg/week deca, 600mg test, 14 weeks. scale went from 98kg to 107kg. Sleep was deep, appetite through the roof, libido stayed decent with test running higher. No PIP worth complaining about. Gear is consistently dosed, my bloodwork backs that up every time

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